ISSN 1662-4009 (online)

ey0019.5-16 | Advances in skeletal biology | ESPEYB19

5.16. Mineralization generates megapascal contractile stresses in collagen fibrils

Ping Hang , Wagermaier Wolfgang , Horbelt Nils , Scoppola Ernesto , Li Chenghao , Werner Peter , Fu Zhengyi , Fatzl Peter

Science 2022 Apr 8;376(6589):188-192.Abstract: https://pubmed-ncbi-nlm-nih-gov/35389802/In Brief: The unique composition of organic and inorganic components allows bone to have remarkable biomechanical properties. This in vitro study reveals the phenomena of large contractile forces during intrafibrillar mineralization explaining the unusual mechanical properties of bone tissue.</p...